<form id="d9991"></form>

        <dfn id="d9991"><listing id="d9991"><mark id="d9991"></mark></listing></dfn>

        會員登陸 / 下載中心
        當前位置:產品目錄 > 抗體 >> 單克隆抗體
        POLI antibody, POLI單抗

        編 號 M-0023
        產品名稱 POLI antibody, POLI單抗
        規 格 0.2ml
        價 格 1980元
        應 用 IHC,WB,ELISA,ICC,IP
        品 牌 Hopebiot

        詳細信息: 說明書下載

        Background:  DNA polymerase activity is essential for replication, repair, recombination and mutagenesis. DNA polymerases can often bypass DNA lesions that block DNA replication, thereby allowing the replication of damaged DNA. One such DNA polymerase is the distributive enzyme DNA pol ι (pol iota), which is encoded by the POLI gene. POLI is located on human chromosome 18q21.2, a region often implicated in the etiology of many human cancers. At thymine templates, DNA Pol ι is highly error-prone when replicating undamaged DNA in that it favors the misincorporation of guanine over the correct nucleotide, adenosine. DNA Pol ι also promotes the replication of damaged DNA by misincorporating deoxynucleotides opposite DNA lesions. DNA Pol ι acts sequentially with DNA Pol ζ, which is essential for damageinduced mutagenesis, to complete the DNA lesion bypass. Therefore, replication involving DNA Pol ι is likely to be highly mutagenic.

        Description: Mouse monoclonal to POLI

        Immunogen: Recombinant human POLI

        Specificity:  ·Reacts with Human, Mouse and Rat.

        ·Isotype: IgG

        Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 108 kDa;

        ·Immunohistochemistry (Frozen/paraffin tissue section): 1/50-100;

        ·Immunocytochemistry: 1/50-100;

        ·ELISA: 1/500;

        ·Optimal working dilutions must be determined by the end user.


        網站首頁 | 公司動態 | 產品中心 | 定制服務 | 代理產品 | 技術專欄 | 客戶留言 | 聯系我們

        Copyright @ 2011 All Rights Reserved 江蘇鎮江厚普生物科技有限公司 備案/許可證編號為:蘇ICP備11043267號

        地址:江蘇省丹陽市呂城工業園 郵編:212300 電子郵箱:hopebiotech@163.com

        訂貨電話:0511-86909515 傳真:0511-86909515 訪問量:13405379   
            <form id="d9991"></form>

              <dfn id="d9991"><listing id="d9991"><mark id="d9991"></mark></listing></dfn>