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    Bcl2 antibody, Bcl-2抗體

     
    編 號 PR-1237
    產品名稱 Bcl2 antibody, Bcl-2抗體
    規 格 0.2ml
    價 格 1980元
    應 用 IHC,WB,ELISA,ICC,IP,IF
    品 牌 Hopebiot

    詳細信息: 說明書下載

    Background:  The Bcl-2 gene was isolated at the chromosomal breakpoint of t(14;18)-bearing follicular B cell lymphomas.Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal.Bcl-2 appears to function in several subcellular locations yet lacks any known motifs that would confer insight into its mechanism of action.A more recently identified protein,designated Bax p21(i.e., Bcl-associated X protein), has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2.Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activty of Bcl-2.

    Description: Rabbit polyclonal to Bcl2

    Immunogen: KLH conjugated synthetic peptide derived from Bcl2

    Specificity:  ·Reacts with Human, Mouse, Pig, Rabbit, Cow, Dog and Rat.

    ·Isotype: IgG

    Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 26 kDa;

    ·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

    ·Immunocytochemistry: 1/100-200;

    ·ELISA: 1/500;

    ·Optimal working dilutions must be determined by the end user.

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